Solid Phase Peptide Synthesizers

Perfecting the chain, simplifying the strain.

From micro-mole research to 600L commercial production — fully automated, GMP-compliant SPPS systems engineered with batch consistency and precision process control at every scale.

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600L

Max Reactor Vol.

SS 316L commercial skid

Pharma References

India's leading manufacturers

21 CFR

Part 11 Compliant

Audit trail, LabVision®

3–6 mo

Delivery Timeline

Based on capacity

Synthesis

Reactors engineered for resin integrity.

Specially designed filter reactors with optimum mixing geometry. Minimum hold up. Efficient drain of complete vessel. Multiport Nitrogen bubbling for filter agitation. Automated lowering system for resin removal. Replaceable PTFE filter.

Every system ships as a complete skid: Amino Acid , Activator , Reagent , Piperidine , Waste vessels etc. including transfer pumps , valves and instrumentation.

Research

Micro-mole to mL

50 – 250 mL

Borosilicate 3.3 Glass

Single & parallel reaction vessel configurations. Micro-mole parallel screening via DFC (6-line / 8-line).

Lab

Bench-scale SPPS

1 L – 10 L

Borosilicate 3.3 Glass

Single & parallel systems (1–3 L and 5–10 L). Compact, cabinet-enclosed with HCS temperature control.

Pilot

Process validation

20 L – 50 L

Glass & SS 316L

Full automation with Hitec Zang LabVision® SCADA. FAT conducted before despatch. Explosion-proof I/O.

Commercial

GMP production

100 L – 1 KL

SS 316L

Multi-vessel elevated platforms. Hydraulic raising/lowering. Full Hitec Zang automation. 21 CFR Part 11.

Engineering Features

What's inside every system.

01 — Transfer

Automated Solvent Transfer

Air-operated PTFE/PFA diaphragm pumps or peristaltic pumps. Volume-based and time-based transfer modes. Complete drain with zero dead space.

02 — Safety

Hazardous Area Ready

Skid-mounted with aluminum-frame glass safety enclosure. Explosion-proof instrumentation. Alarms and safety interlocks designed for hazardous solvent environments.mechanical parts manufactured in-house at Vadodara. Full FAT at factory before despatch. Erection, installation & product trial at client site included.

03 — Thermal

Precise Thermal Control

E3 Tech single-fluid heating/cooling systems (−35 to 200°C). Dedicated machines per reactor for independent temperature management.

04 — Wetted Parts

SS 316L/Glass/PFA/Wetted Paths

Vessels , interconnecting piping , valves and pumps Pneumatically operated glass/PTFE valves. No metal contact with process fluid in glass systems. Vessels , interconnceting piping , valves and pumps.

05 — Data

Complete Data Trail

Logging of all datapoints. Customized batch reports. Multi-axis trend plotter. User comment log. 21 CFR Part 11 audit trail from Hitec Zang LabVision®.

06 — Scope

End-to-end Skid Delivery

Design, manufacture, validate and commission. Mechanical fabrication at Vadodara. FAT at factory, installation and product trial at client site.

Make in India · Delivered Anywhere

All mechanical parts manufactured in-house at Vadodara. Full FAT at factory before despatch. Erection, installation & product trial at client site included.

Automation

Hitec Zang LabVision^®

Recipes run themselves. You just define success.

Drag-and-drop HiBatch recipe editor for coupling, deprotection, washing and transfer sequences. Unlimited recipe storage. Auto and manual mode execution. Full P&ID visualization with live status updates.